Apolipoprotein CIII Overexpression-Induced Hypertriglyceridemia Increases Nonalcoholic Fatty Liver Disease in Association with Inflammation and Cell Death

Figure 8

Effects of apoCIII overexpression and high-fat diet consumption on plasma and liver inflammatory markers. (a) Liver cleaved caspase-1 (), (b) liver IL1ββ (), (c) plasma IL1ββ ( = 4-5), (d) quantification of IL1ββ and CD68 colocalized areas, and (e) representative immunofluorescent confocal microscopy images of IL1ββ and CD68 in liver sections () from NTg and apoCIII mice fed either a low-fat (LF) or high-fat (HF) diets for 16 weeks. Data are expressed as the mean ± SEM. versus HF groups; versus apoCIII mice (; two-way ANOVA).

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