Apolipoprotein CIII Overexpression-Induced Hypertriglyceridemia Increases Nonalcoholic Fatty Liver Disease in Association with Inflammation and Cell Death

Table 3

Food intake; body, liver, and adipose tissue masses; and fasting plasma concentrations of lipids, leptin, and inflammatory markers in NTg and apoCIII mice fed either a low-fat diet (LFD) or a high-fat diet (HFD) for 16 weeks.

	LFD		HFD
	NTg	CIII	NTg	CIII
Food intake (kcal/mouse/day)
	(7)	(7)	(5)	(5)
Body mass (g)
	(17)	(16)	(8)	(6)
Liver (%body weight)
	(17)	(17)	(8)	(8)
Perigonadal WAT (%)
	(10)	(10)	(8)	(8)
Plasma triglycerides (mg/dL)
	(7)	(7)	(7)	(7)
Plasma cholesterol (mg/dL)
	(9)	(7)	(7)	(8)
Nonesterified fatty acids (mEq/L)
	(10)	(8)	(6)	(5)
Plasma leptin (pg/mL)
	(9)	(7)	(6)	(7)
Plasma IL6 (pg/mL)
	(6)	(6)	(7)	(4)
Plasma C-reactive protein (ng/mL)
	(9)	(7)	(7)	(8)

Mean ± SEM (). versus HFD groups; versus apoCIII mice (; two-way ANOVA).