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Oxidative Medicine and Cellular Longevity
Volume 2017 (2017), Article ID 2353729, 12 pages
Research Article

Increased Oxidative Damage of RNA in Early-Stage Nephropathy in db/db Mice

1The MOH Key Laboratory of Geriatrics, Beijing Hospital, National Center of Gerontology, Beijing 100730, China
2Department of Laboratory Medicine, Gansu Provincial Hospital, Lanzhou, Gansu 730000, China
3Graduate School, Chinese Academy of Medical Sciences and Peking Union Medical College, Dongdan, Beijing 100730, China
4Department of Clinical Pharmacy, The People’s Hospital of Lishui, Lishui 323000, China
5Department of Clinical Pharmacy, Ningbo Medical Center Lihuili Eastern Hospital, Ningbo 315000, China
6Department of Nephrology, Beijing Hospital, Ministry of Health, Beijing 100730, China
7Department of Laboratory Medicine, Beijing Hospital of the Ministry of Health, Beijing 100730, China
8Department of Pharmacology, Wenzhou Medical University, University Town, Wenzhou, Zhejiang 325035, China

Correspondence should be addressed to Jian-Ping Cai

Received 15 May 2017; Revised 3 September 2017; Accepted 12 September 2017; Published 19 October 2017

Academic Editor: Aiqing Li

Copyright © 2017 Wan-Xia Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary Table 1s Optimized measurement conditions of DNA from kidney. Supplementary Table 2s Optimized measurement conditions of RNA from kidney. Supplementary Table 3s Optimized measurement conditions of urinary 8-oxoGuo and 8-oxodGuo. Supplementary Table 4s Multiple linear regression analysis between urinary micro-albuminuria and nucleotide acid oxidation markers.

  1. Supplementary Material