Research Article
3-Hydroxykynurenine and 3-Hydroxyanthranilic Acid Enhance the Toxicity Induced by Copper in Rat Astrocyte Culture
Figure 4
Effect of 3-HK and 3-HANA in the cellular dysfunction induced by CuSO4 (350 μM). After 24 h of incubation with 3-HK or 3-HANA (100 μM) + copper, MTT was added to each well and formazan salt was measured. Data are presented as mean values + SEM of 6 independent experiments from 3 different cultures. a versus control and b versus CuSO4 (one-way ANOVA followed by Tukey’s test).