Research Article

Effect of Multicomponent Training on Blood Pressure, Nitric Oxide, Redox Status, and Physical Fitness in Older Adult Women: Influence of Endothelial Nitric Oxide Synthase (NOS3) Haplotypes

Table 4

Effects of 12 weeks of multicomponent training on oxidative stress, antioxidant activity, and physical fitness of 52 older adult women with or without variant genotypes for the eNOS gene at position 894G>T (Glu298Asp).

GluGlu (30)GluAsp + AspAsp (22)
BeforeAfter∆%BeforeAfter∆%

Age (years)62 (8.4)61.8 (9.2)
MDA (μM)5 (1.7)2.8 (1.4)−43.14.8 (1.5)2.3 (0.7)−51.8
GSH (μM)3.6 (0.5)3.7 (0.8)4.83.5 (0.7)3.5 (0.8)0
TAC (μM)0.34 (0.12)0.40 (0.12)17.60.32 (0.08)0.39 (0.12)21.9
EFT (reps)17.5 (3.1)20.4 (4.2)16.816.6 (3.5)19.7 (3.9)18.9
SS (reps)15.3 (3.6)18.6 (4.9)21.513.2 (2.7)16.6 (4.5)25.4
6 min WT (m)515 (66)562 (67)9.1507 (58)556 (49)9.6

Data are reported as means (SD) before and after 12 weeks of multicomponent training for 52 women. MDA = malondialdehyde; GSH = glutathione; TAC = total antioxidant capacity; EFT = elbow flexion test; SS = sit and stand up; 6 min WT = six-minute walk test. compared with before intervention (the same group). Linear mixed-effects models.