An Alginate/Cyclodextrin Spray Drying Matrix to Improve Shelf Life and Antioxidant Efficiency of a Blood Orange By-Product Extract Rich in Polyphenols: MMPs Inhibition and Antiglycation Activity in Dysmetabolic Diseases

Table 4

Inhibitory activity on MMP-2 and MMP-9.

Compounds	IC50 MMP-2 (μg/ml)	IC50 MMP-9 (μg/ml)
ExMR	1.12 ± 0.12	5.52 ± 0.72
ALG	n.a.	n.a.
CD	4.03 ± 0.35^^	2.98 ± 0.31
Hd	n.a.	n.a.
C3G	10.57 ± 1.35^^	7.27 ± 1.05
ExMR2	4.49 ± 0.85^^	4.27 ± 0.46
ALGCDExMR	0.49 ± 0.09^^	1.40 ± 0.19^^

n.a. = not active (IC₅₀ > 100 μg/ml). Reported values are the means ± standard deviation (SD) (). compared to ExMR value. ^{^} compared to ExMR value.