Basic Fibroblast Growth Factor Inhibits Apoptosis and Promotes Proliferation of Adipose-Derived Mesenchymal Stromal Cells Isolated from Patients with Type 2 Diabetes by Reducing Cellular Oxidative Stress

Figure 6

Apoptosis-related gene expression. Real-time RT-PCR analysis of the expression of p21, p53, Bcl-2, Bax, and SIRT1 mRNA in ASCs derived from healthy or diabetic donors, cultured in the presence or absence of bFGF for 7 days. Additionally Bcl-2/Bax mRNA expression ratio was calculated, as it negatively correlates with the size of apoptosis. p value <0.05, p value <0.01, and p value <0.001.