EGCG Prevents High Fat Diet-Induced Changes in Gut Microbiota, Decreases of DNA Strand Breaks, and Changes in Expression and DNA Methylation of Dnmt1 and MLH1 in C57BL/6J Male Mice

Figure 9

Relative CpG methylation status in promoter region of Dnmt1 in colon (a) and liver (b) of C57BL/6J male mice. Mean methylation data are shown relative to control diet. Error bars represent a 95% confidence interval (CD = control diet; HFD = high fat diet; CD + EGCG = control diet plus EGCG; HFD + EGCG = high fat diet plus EGCG. Stars indicate significance: value ≤ 0.05 and value ≤ 0.01).

(a)

(b)