Research Article
A Cystine-Rich Whey Supplement (Immunocal®) Provides Neuroprotection from Diverse Oxidative Stress-Inducing Agents In Vitro by Preserving Cellular Glutathione
Figure 7
Immunocal protects HT22 cells from toxicity induced by overexpression of Aβ1-42. (a) Representative images of HT22 cells transfected with either empty vector (IRES) or Aβ1-42. Top panels display colored images showing successful transfection of the cells, and bottom panels display decolorized images of cell nuclei to visualize nuclear condensation. Arrows indicate transfected cells. (b) Quantification of apoptosis for 4 independent experiments performed as in (a). Results are shown as mean ± SEM, . indicates compared to control, and ††† indicates compared to cells transfected with Aβ1-42 without Immunocal preincubation. Aβ: amyloid-beta; ICAL: Immunocal.
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