Diosmin Attenuates Methotrexate-Induced Hepatic, Renal, and Cardiac Injury: A Biochemical and Histopathological Study in Mice

Figure 5

Histopathologic examination findings of kidney tissue by H&E at ×400. Arrows point to renal tubules. Groups are (a) control group showing normal renal tubules, (b) MTX group showing severe vacuolation, (c) MTX + diosmin 50 mg/kg group showing moderate degeneration, and (d) MTX + diosmin 100 mg/kg showing mild degeneration.

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