Diosmin Attenuates Methotrexate-Induced Hepatic, Renal, and Cardiac Injury: A Biochemical and Histopathological Study in Mice

Table 3

Organ lesion scores in control and different experimental groups.

Lesion	Experimental groups
	Control	MTX	MTX-DM50	MTX-DM100
Hepatic lesions	0.00	3.00 ± 0.00	1.80 ± 0.13^#	1.20 ± 0.13^#
Renal lesions	0.00	3.00 ± 0.00	2.30 ± 0.15^#	1.90 ± 0.31^#
Cardiac lesions	0.00	3.00 ± 0.00	2.00 ± 0.21^#	1.40 ± 0.16^#

Data are expressed as means ± SEM. Significant change at with respect to the negative control group. ^#Significant change at with respect to the MTX group as the positive control group.