Tocotrienol-Rich Fraction Ameliorates Antioxidant Defense Mechanisms and Improves Replicative Senescence-Associated Oxidative Stress in Human Myoblasts

Figure 1

Protective effects of NAC alone and in combination with TRF and ATF on senescent myoblasts. (a) More spindle-shaped cells observed in senescent myoblasts after NAC, TRF + NAC, and ATF + NAC treatment, which were similar to the effect of TRF and ATF treatment alone on senescent myoblasts. Scale bar, 100 μm. (b) The percentage of SA-β-gal positive cells decreased in all treatment groups. Denoting , significantly different compared to the young control, , significantly different compared to the presenescent control, and , significantly different compared to the senescent control. Data are presented as the mean ± SD, .

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