Reactive Oxygen Species Mediated Prostaglandin E₂ Contributes to Acute Response of Epithelial Injury

Figure 2

Scratching-injury-induced PGE₂ production and the despondence on ROS. (a) PGE₂ secretion by HaCat cells after scratches. PGE₂ was measured by ELISA in different periods of time as indicated. (b) Suppressed secretion PGE₂ by NOX/ROS inhibitor. Values are means ± SEMs of three replicates. and # indicate compared with undamaged control cells and with scratched cells, respectively.

(a)

(b)