Biotransformation of <i>Dioscorea nipponica</i> by Rat Intestinal Microflora and Cardioprotective Effects of Diosgenin

<div>Effects of diosgenin and <i>Dioscorea nipponica</i> extract on acute experimental myocardial ischemia and treatment percentage. (i) (a–e) SOD, CAT, GPx, T-AOC, and MDA serum levels. (ii) (f) Treatment percentage of assay markers for each treatment group. Normal: normal control; ISO: model group only injected with isoprenaline; POS: positive control (propranolol, 10 mg/kg); Diosgenin L, Diosgenin M, and Diosgenin H: orally given diosgenin 20, 40, and 80 mg/kg of low, medium and high dose, respectively, after ISO injection; DN extract: orally given <i>Dioscorea nipponica</i> extract (500 mg/kg), after ISO injection. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: Biotransformation of <i>Dioscorea nipponica</i> by Rat Intestinal Microflora and Cardioprotective Effects of Diosgenin 

Oxidative Medicine and Cellular Longevity

Biotransformation of Dioscorea nipponica by Rat Intestinal Microflora and Cardioprotective Effects of Diosgenin

Figure 4