TBHQ Alleviated Endoplasmic Reticulum Stress-Apoptosis and Oxidative Stress by PERK-Nrf2 Crosstalk in Methamphetamine-Induced Chronic Pulmonary Toxicity

<div>Effect of TBHQ on the lasting ERS chronically exposed to MA. (a) GRP78 expression in rat lungs by western blot; (b) GRP78 protein expression illustrated by immunohistochemical analysis (×400). Cross sections were stained with rabbit anti-GRP78 (brown) and counterstained with hematoxylin (blue) in different groups. 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MA: methamphetamine; THBQ: tertiary butylhydroquinone.</div>

Oxidative Medicine and Cellular Longevity

fig3

Figure 3

Figure 3: TBHQ Alleviated Endoplasmic Reticulum Stress-Apoptosis and Oxidative Stress by PERK-Nrf2 Crosstalk in Methamphetamine-Induced Chronic Pulmonary Toxicity 

Figure 3 | TBHQ Alleviated Endoplasmic Reticulum Stress-Apoptosis and Oxidative Stress by PERK-Nrf2 Crosstalk in Methamphetamine-Induced Chronic Pulmonary Toxicity 