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Oxidative Medicine and Cellular Longevity
Volume 2017 (2017), Article ID 4386947, 16 pages
https://doi.org/10.1155/2017/4386947
Research Article

Hypoxia Downregulates MAPK/ERK but Not STAT3 Signaling in ROS-Dependent and HIF-1-Independent Manners in Mouse Embryonic Stem Cells

1Institute of Experimental Biology, Faculty of Science, Masaryk University, Kotlářská 267/2, 61137 Brno, Czech Republic
2Institute of Biophysics, Academy of Sciences of the Czech Republic, Královopolská 2590/135, 61200 Brno, Czech Republic
3International Clinical Research Center, Centre of Biomolecular and Cellular Engineering, St. Anne’s University Hospital, Pekařská 53, 65691 Brno, Czech Republic

Correspondence should be addressed to Jiří Pacherník; zc.inum.ics@apij

Received 18 January 2017; Revised 27 April 2017; Accepted 15 May 2017; Published 27 July 2017

Academic Editor: Magdalena Skonieczna

Copyright © 2017 Jan Kučera et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Jan Kučera, Julie Netušilová, Stanislava Sladeček, et al., “Hypoxia Downregulates MAPK/ERK but Not STAT3 Signaling in ROS-Dependent and HIF-1-Independent Manners in Mouse Embryonic Stem Cells,” Oxidative Medicine and Cellular Longevity, vol. 2017, Article ID 4386947, 16 pages, 2017. doi:10.1155/2017/4386947