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Oxidative Medicine and Cellular Longevity
Volume 2017, Article ID 4517486, 13 pages
https://doi.org/10.1155/2017/4517486
Research Article

Tanshinone IIA Inhibits Glutamate-Induced Oxidative Toxicity through Prevention of Mitochondrial Dysfunction and Suppression of MAPK Activation in SH-SY5Y Human Neuroblastoma Cells

1Center for Bioresources & Drug Discovery and School of Biosciences & Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou 510006, China
2School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China
3Hunan Auragene Biotech Co., Ltd., Changsha 410013, China
4Guangdong Province Key Laboratory for Biotechnology Drug Candidates, Guangdong Pharmaceutical University, Guangzhou 510006, China

Correspondence should be addressed to Zebo Huang; nc.ude.updg@gnauhobez

Received 28 January 2017; Revised 17 April 2017; Accepted 2 May 2017; Published 11 June 2017

Academic Editor: Giuseppe Filomeni

Copyright © 2017 Haifeng Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [3 citations]

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  • Brice Wilfried Obiang-Obounou, Kyu-Seok Hwang, Jong-Soon Choi, Byeong-Churl Jang, Yu-Kyoung Park, Jinho Lee, Tae-Yun Lee, Myung-Ae Bae, and Kyung-Bok Lee, “Anti-adipogenic effects on 3T3-L1 cells and zebrafish by tanshinone IIA,” International Journal of Molecular Sciences, vol. 18, no. 10, 2017. View at Publisher · View at Google Scholar
  • Lorenzo Di Cesare Mannelli, Marialuisa Piccolo, Francesco Maione, Maria Grazia Ferraro, Carlo Irace, Vincenzo De Feo, Carla Ghelardini, and Nicola Mascolo, “Tanshinones from Salvia miltiorrhiza Bunge revert chemotherapy-induced neuropathic pain and reduce glioblastoma cells malignancy,” Biomedicine & Pharmacotherapy, vol. 105, pp. 1042–1049, 2018. View at Publisher · View at Google Scholar
  • Anat Elmann, Alona Telerman, Rivka Ofir, Yoel Kashman, and Orly Lazarov, “β-amyloid cytotoxicity is prevented by natural achillolide A,” Journal of Natural Medicines, 2018. View at Publisher · View at Google Scholar