Table of Contents Author Guidelines Submit a Manuscript
Oxidative Medicine and Cellular Longevity
Volume 2017 (2017), Article ID 4523673, 12 pages
https://doi.org/10.1155/2017/4523673
Research Article

Experimental and Clinical Applications of Chamaecyparis obtusa Extracts in Dry Eye Disease

1The Affiliated Eye Hospital, Wenzhou Medical University, Wenzhou, China
2Department of Ophthalmology and Center for Creative Biomedical Scientists, Chonnam National University, Gwangju, Republic of Korea
3Balgeun Eye Clinic 21, Gwangju, Republic of Korea
4College of Veterinary Medicine and BK 21 PLUS Project Team, Chonnam National University, Gwangju, Republic of Korea
5Business Supporting Team, Center for Nano Bio Research, Jangseong, Jeonnam, Republic of Korea
6Jeonnam Forest Resource Research Institute, Naju, Jeonnam, Republic of Korea

Correspondence should be addressed to Kyung Chul Yoon; rk.ca.unj@nooyck

Received 28 February 2017; Revised 22 September 2017; Accepted 27 September 2017; Published 26 December 2017

Academic Editor: Steven McAnulty

Copyright © 2017 Lian Cui et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. “The definition and classification of dry eye disease: report of the Definition and Classification Subcommittee of the International Dry Eye WorkShop (2007),” The Ocular Surface, vol. 5, no. 2, pp. 75–92, 2007. View at Publisher · View at Google Scholar
  2. A. J. Paulsen, K. J. Cruickshanks, M. E. Fischer et al., “Dry eye in the beaver dam offspring study: prevalence, risk factors, and health-related quality of life,” American Journal of Ophthalmology, vol. 157, no. 4, pp. 799–806, 2014. View at Publisher · View at Google Scholar · View at Scopus
  3. M. S. Sung, Z. Li, L. Cui et al., “Effect of topical 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside in a mouse model of experimental dry eye,” Investigative Ophthalmology & Visual Science, vol. 56, no. 5, pp. 3149–3158, 2015. View at Publisher · View at Google Scholar · View at Scopus
  4. V. L. Perez, S. C. Pflugfelder, S. Zhang, A. Shojaei, and R. Haque, “Lifitegrast, a novel integrin antagonist for treatment of dry eye disease,” The Ocular Surface, vol. 14, no. 2, pp. 207–215, 2016. View at Publisher · View at Google Scholar · View at Scopus
  5. Z. Li, J. H. Choi, H. J. Oh, S. H. Park, J. B. Lee, and K. C. Yoon, “Effects of eye drops containing a mixture of omega-3 essential fatty acids and hyaluronic acid on the ocular surface in desiccating stress-induced murine dry eye,” Current Eye Research, vol. 39, no. 9, pp. 871–878, 2014. View at Publisher · View at Google Scholar · View at Scopus
  6. W. Choi, J. B. Lee, L. Cui et al., “Therapeutic efficacy of topically applied antioxidant medicinal plant extracts in a mouse model of experimental dry eye,” Oxidative Medicine and Cellular Longevity, vol. 2016, Article ID 4727415, 10 pages, 2016. View at Publisher · View at Google Scholar · View at Scopus
  7. A. Higuchi, K. Takahashi, M. Hirashima, T. Kawakita, and K. Tsubota, “Selenoprotein P controls oxidative stress in cornea,” PLoS One, vol. 5, no. 3, article e9911, 2010. View at Publisher · View at Google Scholar · View at Scopus
  8. J. Li, D. Ruzhi, X. Hua et al., “Blueberry component pterostilbene protects corneal epithelial cells from inflammation via anti-oxidative pathway,” Scientific Reports, vol. 6, no. 1, article 19408, 2016. View at Publisher · View at Google Scholar · View at Scopus
  9. T. H. Wakamatsu, M. Dogru, and K. Tsubota, “Tearful relations: oxidative stress, inflammation and eye diseases,” Arquivos Brasileiros de Oftalmologia, vol. 71, Supplementary, no. 6, pp. 72–79, 2008. View at Publisher · View at Google Scholar
  10. Y. Uchino, T. Kawakita, M. Miyazawa et al., “Oxidative stress induced inflammation initiates functional decline of tear production,” PLoS One, vol. 7, no. 10, article e45805, 2012. View at Publisher · View at Google Scholar · View at Scopus
  11. Y. Uchino, T. Kawakita, T. Ishii, N. Ishii, and K. Tsubota, “A new mouse model of dry eye disease: oxidative stress affects functional decline in the lacrimal gland,” Cornea, vol. 31, Supplement 1, pp. S63–S67, 2012. View at Publisher · View at Google Scholar · View at Scopus
  12. C. Amico, T. Tornetta, C. Scifo, and A. R. Blanco, “Antioxidant effect of 0.2% xanthan gum in ocular surface corneal epithelial cells,” Current Eye Research, vol. 40, no. 1, pp. 72–76, 2015. View at Publisher · View at Google Scholar · View at Scopus
  13. P. S. Larmo, R. L. Jarvinen, N. L. Setala et al., “Oral sea buckthorn oil attenuates tear film osmolarity and symptoms in individuals with dry eye,” The Journal of Nutrition, vol. 140, no. 8, pp. 1462–1468, 2010. View at Publisher · View at Google Scholar · View at Scopus
  14. S. D. Hsu, D. P. Dickinson, H. Qin et al., “Green tea polyphenols reduce autoimmune symptoms in a murine model for human Sjogren’s syndrome and protect human salivary acinar cells from TNF-α-induced cytotoxicity,” Autoimmunity, vol. 40, no. 2, pp. 138–147, 2007. View at Publisher · View at Google Scholar · View at Scopus
  15. J. B. Lee, S. H. Kim, S. C. Lee et al., “Blue light-induced oxidative stress in human corneal epithelial cells: protective effects of ethanol extracts of various medicinal plant mixtures,” Investigative Ophthalmology & Visual Science, vol. 55, no. 7, pp. 4119–4127, 2014. View at Publisher · View at Google Scholar · View at Scopus
  16. W. Choi, J. C. Kim, W. S. Kim et al., “Clinical effect of antioxidant glasses containing extracts of medicinal plants in patients with dry eye disease: a multi-center, prospective, randomized, double-blind, placebo-controlled trial,” PLoS One, vol. 10, no. 10, article e0139761, 2015. View at Publisher · View at Google Scholar · View at Scopus
  17. S.-C. Chien, J.-Y. Chang, C.-C. Kuo, C.-C. Hsieh, N.-S. Yang, and Y.-H. Kuo, “Cytotoxic and novel skeleton compounds from the heartwood of Chamaecyparis obtusa var. formosana,” Tetrahedron Letters, vol. 48, no. 9, pp. 1567–1569, 2007. View at Publisher · View at Google Scholar · View at Scopus
  18. S. S. Cheng, H. T. Chang, C. L. Wu, and S. T. Chang, “Anti-termitic activities of essential oils from coniferous trees against Coptotermes formosanus,” Bioresource Technology, vol. 98, no. 2, pp. 456–459, 2007. View at Publisher · View at Google Scholar · View at Scopus
  19. P. Marimuthu, C.-L. Wu, H.-T. Chang, and S.-T. Chang, “Antioxidant activity of the ethanolic extract from the bark of Chamaecyparis obtusa var. formosana,” Journal of the Science of Food and Agriculture, vol. 88, no. 8, pp. 1400–1405, 2008. View at Publisher · View at Google Scholar · View at Scopus
  20. S. C. Cheng, W. H. Li, Y. C. Shi et al., “Antioxidant activity and delayed aging effects of hot water extract from Chamaecyparis obtusa var. formosana leaves,” Journal of Agricultural and Food Chemistry, vol. 62, no. 18, pp. 4159–4165, 2014. View at Publisher · View at Google Scholar · View at Scopus
  21. B. S. An, J. H. Kang, H. Yang et al., “Anti-inflammatory effects of essential oils from Chamaecyparis obtusa via the cyclooxygenase-2 pathway in rats,” Molecular Medicine Reports, vol. 8, no. 1, pp. 255–259, 2013. View at Publisher · View at Google Scholar · View at Scopus
  22. E. J. Jeong, L. Hwang, M. Lee, K. Y. Lee, M. J. Ahn, and S. H. Sung, “Neuroprotective biflavonoids of Chamaecyparis obtusa leaves against glutamate-induced oxidative stress in HT22 hippocampal cells,” Food and Chemical Toxicology, vol. 64, pp. 397–402, 2014. View at Publisher · View at Google Scholar · View at Scopus
  23. E.-J. Hong, K.-J. Na, I.-G. Choi, K.-C. Choi, and E.-B. Jeung, “Antibacterial and antifungal effects of essential oils from coniferous trees,” Biological and Pharmaceutical Bulletin, vol. 27, no. 6, pp. 863–866, 2004. View at Publisher · View at Google Scholar · View at Scopus
  24. D. Bae, H. Seol, H. G. Yoon et al., “Inhaled essential oil from Chamaecyparis obtuse ameliorates the impairments of cognitive function induced by injection of β-amyloid in rats,” Pharmaceutical Biology, vol. 50, no. 7, pp. 900–910, 2012. View at Publisher · View at Google Scholar · View at Scopus
  25. S. S. Joo, Y. M. Yoo, S. H. Ko et al., “Effects of essential oil from Chamaecypris obtusa on the development of atopic dermatitis-like skin lesions and the suppression of Th cytokines,” Journal of Dermatological Science, vol. 60, no. 2, pp. 122–125, 2010. View at Publisher · View at Google Scholar · View at Scopus
  26. H. Park, H. Lee, M. Shin et al., “Effects of cosolvents on the decaffeination of green tea by supercritical carbon dioxide,” Food Chemistry, vol. 105, no. 3, pp. 1011–1017, 2007. View at Publisher · View at Google Scholar · View at Scopus
  27. P. Sookwong, P. Suttiarporn, P. Boontakham, P. Seekhow, S. Wangtueai, and S. Mahatheeranont, “Simultaneous quantification of vitamin E, γ-oryzanols and xanthophylls from rice bran essences extracted by supercritical CO2,” Food Chemistry, vol. 211, pp. 140–147, 2016. View at Publisher · View at Google Scholar · View at Scopus
  28. Z. Li, L. Cui, J. M. Yang et al., “The wound healing effects of adiponectin eye drops after corneal alkali burn,” Current Eye Research, vol. 41, no. 11, pp. 1424–1432, 2016. View at Publisher · View at Google Scholar · View at Scopus
  29. N. Chatterjee, H. J. Eom, and J. Choi, “A systems toxicology approach to the surface functionality control of graphene-cell interactions,” Biomaterials, vol. 35, no. 4, pp. 1109–1127, 2014. View at Publisher · View at Google Scholar · View at Scopus
  30. Y. Xu, S. Wang, Q. Miao et al., “Protective role of hinokitiol against H2O2-induced injury in human corneal epithelium,” Current Eye Research, vol. 42, no. 1, pp. 47–53, 2016. View at Publisher · View at Google Scholar
  31. Z. Li, J. M. Woo, S. W. Chung et al., “Therapeutic effect of topical adiponectin in a mouse model of desiccating stress-induced dry eye,” Investigative Ophthalmology & Visual Science, vol. 54, no. 1, pp. 155–162, 2013. View at Publisher · View at Google Scholar · View at Scopus
  32. K. C. Yoon, K. Y. Ahn, W. Choi et al., “Tear production and ocular surface changes in experimental dry eye after elimination of desiccating stress,” Investigative Ophthalmology & Visual Science, vol. 52, no. 10, pp. 7267–7273, 2011. View at Publisher · View at Google Scholar · View at Scopus
  33. R. M. Schiffman, M. D. Christianson, G. Jacobsen, J. D. Hirsch, and B. L. Reis, “Reliability and validity of the ocular surface disease index,” Archives of Ophthalmology, vol. 118, no. 5, pp. 615–621, 2000. View at Publisher · View at Google Scholar
  34. K. C. Yoon, H. Heo, S. K. Im, I. C. You, Y. H. Kim, and Y. G. Park, “Comparison of autologous serum and umbilical cord serum eye drops for dry eye syndrome,” American Journal of Ophthalmology, vol. 144, no. 1, pp. 86–92.e2, 2007. View at Publisher · View at Google Scholar · View at Scopus
  35. H. J. Park, S. K. Kim, W. S. Kang, J. M. Woo, and J. W. Kim, “Effects of essential oil from Chamaecyparis obtusa on cytokine genes in the hippocampus of maternal separation rats,” Canadian Journal of Physiology and Pharmacology, vol. 92, no. 2, pp. 95–101, 2014. View at Publisher · View at Google Scholar · View at Scopus
  36. T. P. Devasaqayam, J. C. Tilak, K. K. Boloor, K. S. Sane, S. S. Ghaskadbi, and R. D. Lele, “Free radicals and antioxidants in human health: currents status and future prospects,” The Journal of the Association of Physicians of India, vol. 52, pp. 794–804, 2004. View at Google Scholar
  37. T. C. Chien, S. F. Lo, and C. L. Ho, “Chemical composition and anti-inflammatory activity of Chamaecyparis obtusa f.formosana wood essential oil from Taiwan. Nature product,” Communications, vol. 9, no. 5, p. 723, 2014. View at Google Scholar
  38. R. Deng, X. Hua, J. Li et al., “Oxidative stress markers induced by hyperosmolarity in primary human corneal epithelial cells,” PLoS One, vol. 10, no. 5, article e0126561, 2015. View at Publisher · View at Google Scholar · View at Scopus
  39. T. H. Wakamatsu, M. Dogru, Y. Matsumoto et al., “Evaluation of lipid oxidative stress status in Sjögren syndrome patients,” Investigative Ophthalmology & Visual Science, vol. 54, no. 1, pp. 201–210, 2013. View at Publisher · View at Google Scholar · View at Scopus
  40. K. Tsubota, M. Kawashima, T. Inaba et al., “The antiaging approach for the treatment of dry eye,” Cornea, vol. 31, Supplement 1, pp. S3–S8, 2012. View at Publisher · View at Google Scholar · View at Scopus
  41. Q. Le, K. Tabuchi, E. Warabi, and A. Hara, “The role of peroxiredoxin I in cisplatin-induced ototoxicity,” Auris Nasus Larynx, vol. 44, no. 2, pp. 205–212, 2017. View at Publisher · View at Google Scholar · View at Scopus
  42. T. Ma, T. Chen, P. Li et al., “Heme oxygenase-1 (HO-1) protects human lens epithelial cells (SRA01/04) against hydrogen peroxide (H2O2)-induced oxidative stress and apoptosis,” Experimental Eye Research, vol. 146, pp. 318–329, 2016. View at Publisher · View at Google Scholar · View at Scopus
  43. Y. Wei, N. Gadaria-Rathod, S. Epstein, and P. Asbell, “Tear cytokine profile as a noninvasive biomarker of inflammation for ocular surface diseases: standard operating procedures,” Investigative Ophthalmology & Visual Science, vol. 54, no. 13, pp. 8327–8336, 2013. View at Publisher · View at Google Scholar
  44. Y. Wang, W. Yu, C. Shen et al., “Predictive value of serum IFN-γ inducible protein-10 and IFN-γ/IL-4 ratio for liver fibrosis progression in CHB patients,” Scientific Reports, vol. 7, article 40404, 2017. View at Publisher · View at Google Scholar
  45. A. Olenik, “Effectiveness and tolerability of dietary supplementation with a combination of omega-3 polyunsaturated fatty acids and antioxidants in the treatment of dry eye symptoms: results of a prospective study,” Clinical Ophthalmology, vol. 8, pp. 169–176, 2014. View at Publisher · View at Google Scholar · View at Scopus
  46. E. C. Kim, J. S. Choi, and C. K. Joo, “A comparison of vitamin A and cyclosporine A 0.05% eye drops for treatment of dry eye syndrome,” American Journal of Ophthalmology, vol. 147, no. 2, pp. 206–213.e3, 2009. View at Publisher · View at Google Scholar · View at Scopus