Oxidative Medicine and Cellular Longevity / 2017 / Article / Fig 7

Research Article

Baicalin Ameliorates Liver Injury Induced by Chronic plus Binge Ethanol Feeding by Modulating Oxidative Stress and Inflammation via CYP2E1 and NRF2 in Mice

Figure 7

Baicalin prevents chronic-binge ethanol-induced liver injury by modulating NRF2 and its target genes HO-1 and NQO1. (a) Western blot analyses of nuclear extracts of NRF2 along with loading control histone H3. Hepatic mRNA of HO-1 and NQO1 was analyzed by real-time PCR. The results are expressed as fold change relative to the pair-fed group. Values represent means ± SEM and /group. versus pair-fed group, # versus EtOH group.

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