Blockage of NOX2/MAPK/NF-κB Pathway Protects Photoreceptors against Glucose Deprivation-Induced Cell Death

Figure 3

Inhibition of NOX2 increases viability of 661W cells. (a) 661W cells were cultured in glucose-free medium for indicated times, and cell viability was determined with the MTT assay. (b) 661W cells were cultured in glucose-free medium for 16 h in the presence of APO or NSC (50–150 μM), and cell viability was determined with the MTT assay. The results are presented as means ± SEM (, compared to the vehicle group; one-way ANOVA and Bonferroni test).

(a)

(b)