Neuroprotective and Memory-Enhancing Effect of the Combined Extract of Purple Waxy Corn Cob and Pandan in Ovariectomized Rats

Figure 3

The effect of the PCP on the density of survival neurons in medial prefrontal cortex (mPFC) (/group). The upper panel showed the photomicrograph of the coronal section of rat brains in (a) naïve control, (b) sham operation + vehicle, (c) OVX + vehicle, (d) OVX + donepezil, (e) OVX + isoflavone, (f) OVX + PCP 20 mg/kg BW, (g) OVX + PCP 40 mg/kg BW, and (h) OVX + PCP 80 mg/kg BW. Scale bar: 20 μm. The lower panel demonstrated the density of survival neurons of mPFC. ^a value < 0.05, compared with the sham operation group. value < 0.05 and 0.01, respectively, compared with the OVX + vehicle-treated group. Data were expressed as mean ± SEM.