Neuroprotective and Memory-Enhancing Effect of the Combined Extract of Purple Waxy Corn Cob and Pandan in Ovariectomized Rats
Table 2
The effect of PCP on oxidative stress markers in the prefrontal cortex (/group).
Oxidative stress markers in the prefrontal cortex
Treatment
MDA
GSH-Px
SOD
CAT
(nmol/mg protein)
(Units/mg protein)
(Units/mg protein)
(Units/mg protein)
Naïve control
0.073 ± 0.0.001
0.661 ± 0.034
0.567 ± 0.164
2.707 ± 0.234
Sham operation
0.077 ± 0.007
0.576 ± 0.052
0.834 ± 0.256
2.516 ± 0.237
OVX + vehicle
0.095 ± 0.008a
0.523 ± 0.034
0.309 ± 0.100
2.684 ± 0.216
OVX + donepezil 3 mg/kg BW
0.090 ± 0.007
0.714 ± 0.047
1.387 ± 0.344
2.650 ± 0.187
OVX + isoflavone 20 mg/kg BW
0.059 ± 0.005
0.902 ± 0.111
2.220 ± 0.458
2.130 ± 0.210
OVX + PCP 20 mg/kg BW
0.047 ± 0.012
0.866 ± 0.186
3.080 ± 0.352
2.447 ± 0.359
OVX + PCP 40 mg/kg BW
0.034 ± 0.002
0.799 ± 0.070
2.047 ± 0.184
2.151 ± 0.160
OVX + PCP 80 mg/kg BW
0.032 ± 0.004
0.639 ± 0.029
1.068 ± 0.366
1.921 ± 0.092
a value < 0.05, compared with the sham operation group. value < 0.05, 0.01, and 0.001, respectively, compared with the OVX + vehicle-treated group. Data were expressed as mean ± SEM.
