Probucol Reduces Testicular Torsion/Detorsion-Induced Ischemia/Reperfusion Injury in Rats

Figure 4

Microphotographs of cross sections of the seminiferous tubules in the control, ischemia-reperfusion, and treatment groups (hematoxylin and eosin staining, original magnification ×200). (a) Bilateral testes in the control group and contralateral testes in the ischemia-reperfusion and treatment groups all displayed normal seminiferous tubular diameter, germ cell layer number, and spermatogenesis from spermatogonium to spermatozoon. The germinal epithelium left an open lumen at the center of seminiferous tubule. (b) The ipsilateral testes in the ischemia-reperfusion group indicated atrophic seminiferous tubules, decreased germ cell layer number, and arrested spermatogenesis. (c) The ipsilateral testes in the treatment group showed nearly normal seminiferous tubule, but germinal epithelial cells sloughed into the tubular lumen (arrow), which easily occluded the seminiferous tubule.

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