Hederagenin Induces Apoptosis in Cisplatin-Resistant Head and Neck Cancer Cells by Inhibiting the Nrf2-ARE Antioxidant Pathway

<div>Hederagenin decreases the viability of HNC cells. (a) The structure of hederagenin. (b, c) Cell viability was assessed in cisplatin-sensitive and cisplatin-resistant HNC cell lines exposed to various concentrations of hederagenin for 72 h. (d) Images of hederagenin-treated and hederagenin-nontreated (NT) cisplatin-resistant HNC cells.</div>

Oxidative Medicine and Cellular Longevity

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Figure 1

Figure 1: Hederagenin Induces Apoptosis in Cisplatin-Resistant Head and Neck Cancer Cells by Inhibiting the Nrf2-ARE Antioxidant Pathway 