Oxidative Medicine and Cellular Longevity / 2017 / Article / Fig 5

Review Article

Metallothionein in Brain Disorders

Figure 5

Representative images of the immunohistochemical study of MT in the hippocampus of rats treated with KA. Control rats (a, c) and rats treated with KA (b, d). (a, c) A normal structure of pyramidal cells and astrocytes (↑) in untreated animals. (b, d) Neurons with pyrolysis (), pyknotic (N), and neuropil neurons are observed with the presence of interstitial edema in the hippocampus of experimental rats. In the astrocytes (↑) of the rats treated with KA, an increase of the immunoreactivity of the MT (brown color) can be observed. Magnification (a, b) 400x and (c, d) 1000x.

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