Research Article

Cultivation and Immortalization of Human B-Cells Producing a Human Monoclonal IgM Antibody Binding to MDA-LDL: Further Evidence for Formation of Atherogenic MDA-LDL Adducts in Humans In Vivo

Figure 1

Schematic overview of the process of human monoclonal antibody production. The fusion of human B-cells with murine myeloma cells results in immortalized hybridomas producing human monoclonal antibodies.