Research Article
Salvianolic Acid A Inhibits OX-LDL Effects on Exacerbating Choroidal Neovascularization via Downregulating CYLD
Figure 10
Sal A modulates CYLD via PI3K/AKT/mTOR pathway. (a) Our former study proved that Sal A promoted ERK and PI3K/AKT/mTOR phosphorylation in ARPE-19 cells after 48 hours. (b) Western blot results of CYLD showing that PI3k and mTOR inhibitor abolished Sal A-induced CYLD downregulation. (c) Quantitative densitometry results of western blot. Data are expressed as means ± ESM. versus the control and OX-LDL + Sal A group.
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