Mitochondria-Targeted Antioxidant SkQ1 Improves Dermal Wound Healing in Genetically Diabetic Mice

Figure 1

SkQ1 accelerates wound closure in diabetic mice. Full-thickness excisional skin wounds were created surgically in the interscapular area on the back of nondiabetic (db/++, ), diabetic (db/db, ), and diabetic mice receiving SkQ1 (250 nmol/kg of body mass per day) during 12 weeks (). (a) Representative images of the wounds, (b) dynamics of the wound closure. Data are presented as mean ± SEM; for SkQ1-treated versus untreated diabetic mice. ^‡ for the untreated diabetic mice versus nondiabetic mice.

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