Semipurified Ethyl Acetate Partition of Methanolic Extract of Melastoma malabathricum Leaves Exerts Gastroprotective Activity Partly via Its Antioxidant-Antisecretory-Anti-Inflammatory Action and Synergistic Action of Several Flavonoid-Based Compounds

Table 4

Gastroprotective effect of various partitions of MEMM against ethanol-induced in rats.

Pretreatment	Dose; (mg/kg)	Ulcer area; (mm^2)	Gastroprotection (%)
10% DMSO	—	27.00 ± 0.71	—
Ranitidine	100 mg	9.80 ± 1.11	63.70
PEMM	50 mg	23.60 ± 1.36	12.59
	250 mg	18.00 ± 0.71	33.33
	500 mg	12.40 ± 0.68	54.07
EAMM	50 mg	19.80 ± 1.07	26.67
	250 mg	10.00 ± 1.18	62.96
	500 mg	0.80 ± 0.20	97.04
AQMM	50 mg	22.80 ± 0.86	15.56
	250 mg	15.40 ± 0.68	42.96
	500 mg	3.80 ± 0.37	85.93

Data were expressed as mean ± SEM and analyzed by one-way ANOVA followed by Dunnett’s post hoc test ().
as compared to control (10% DMSO).