Fucoxanthin, a Marine Carotenoid, Attenuates β-Amyloid Oligomer-Induced Neurotoxicity Possibly via Regulating the PI3K/Akt and the ERK Pathways in SH-SY5Y Cells

Figure 2

Fucoxanthin attenuates Aβ oligomer-induced neuronal loss as evidenced by FDA/PI double staining. SH-SY5Y cells were treated with 3 μM fucoxanthin. After 2 h, 1 μM Aβ oligomer was added. FDA/PI double staining was used to demonstrate FDA-positive viable cells and PI-positive nonviable cells at 24 h after the treatment of Aβ oligomers.