Research Article

Estrogens Protect Calsequestrin-1 Knockout Mice from Lethal Hyperthermic Episodes by Reducing Oxidative Stress in Muscle

Figure 2

Changes in absolute core temperature in mice subjected to heat stress protocol. (a) Increase in absolute core temperature, recorded every 5 min, during exposure to heat stress protocol in male and female CASQ1-null mice, either untreated or treated with Premarin (males) and leuprolide (females). (b) Semilog plots showing results of repeated measures ANOVA with post hoc Tukey test. Data are given as mean ± SEM; n = number of mice. See also Table S3.
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