Picroside II Shows Protective Functions for Severe Acute Pancreatitis in Rats by Preventing NF-κB-Dependent Autophagy

Figure 6

Hematoxylin and eosin (H&E) stain analysis for the effects of treat time on pancreas tissues of rats. C3, C6, and C12, the healthy rats were treated with 25 mg/kg 0.9% saline solution for 3, 6, and 12 h, respectively. M3, M6, and M12, the SAP models were treated with 25 mg/kg 0.9% saline solution for 3, 6, and 12 h, respectively. P3, P6, and P12, SAP models were treated with 25 mg/kg picroside II for 3, 6, and 12 h, respectively. Data were presented as means ± SD from five independent experiments. versus the control group; ^# versus the picroside II-treated group (25 mg/kg).