(a)
(b)
(c)
Figure 2: (a) Representative path tracings of the Morris water maze. A: sham group (A1, first day first trial; A2, probe trial); B: OVX group (B1, first day first trial; B2, probe trial); C: estrogen group (C1, first day first trial; C2, probe trial); D: EBNH group (D1, first day first trial; D2, probe trial); E: EBNM group (E1, first day first trial; E2, probe trial); F: EBNL group (F1, first day first trial; F2, probe trial). (b) Time in the target quadrant in the probe trial; (c) latency to the first entry to the target quadrant. A compared with OVX group; B compared with sham group for spending time in the target quadrant and latency to the first entry to the target quadrant (ANOVA). OVX: ovariectomized. Groups are the same as in Figure 1.