Research Article
Blood-Based Bioenergetic Profiling Reflects Differences in Brain Bioenergetics and Metabolism
Table 5
Pearson and partial correlations between monocyte respiration and brain glucose metabolism (FDG-PET).
| FDG-PET: brain region | Maximal | Reserve | BHI | R | p | R | p | R | p |
| Pearson | | | | | | | Area 24 | 0.46 | 0.44 | 0.26 | 0.67 | 0.40 | 0.50 | Area 25 | 0.39 | 0.51 | 0.19 | 0.75 | 0.41 | 0.50 | Area 32 | 0.50 | 0.39 | 0.28 | 0.64 | 0.43 | 0.46 | Amygdala | 0.42 | 0.48 | 0.23 | 0.71 | 0.28 | 0.65 | Ant. hippocampus | 0.46 | 0.44 | 0.31 | 0.61 | 0.26 | 0.68 | Post. hippocampus | 0.39 | 0.52 | 0.27 | 0.66 | 0.18 | 0.77 | Frontal cortex | 0.32 | 0.59 | 0.06 | 0.93 | 0.37 | 0.55 | Partial for age | | | | | | | Area 24 | 0.46 | 0.54 | 0.16 | 0.84 | 0.92 | 0.08 | Area 25 | 0.38 | 0.62 | 0.08 | 0.92 | 0.89 | 0.11 | Area 32 | 0.50 | 0.50 | 0.19 | 0.81 | 0.93 | 0.07 | Amygdala | 0.45 | 0.55 | 0.08 | 0.92 | 0.96 | 0.04 | Ant. hippocampus | 0.49 | 0.51 | 0.20 | 0.80 | 0.91 | 0.09 | Post. hippocampus | 0.42 | 0.58 | 0.13 | 0.87 | 0.89 | 0.11 | Frontal cortex | 0.31 | 0.69 | −0.12 | 0.88 | 0.96 | 0.04 | Partial for weight | | | | | | | Area 24 | 0.11 | 0.89 | 0.04 | 0.96 | 0.36 | 0.64 | Area 25 | 0.05 | 0.95 | −0.02 | 0.98 | 0.36 | 0.64 | Area 32 | 0.16 | 0.84 | 0.06 | 0.94 | 0.40 | 0.60 | Amygdala | −0.07 | 0.93 | −0.07 | 0.93 | 0.20 | 0.80 | Ant. hippocampus | 0.07 | 0.93 | 0.10 | 0.90 | 0.17 | 0.83 | Post. hippocampus | −0.03 | 0.97 | 0.04 | 0.96 | 0.07 | 0.93 | Frontal cortex | −0.26 | 0.74 | −0.35 | 0.65 | 0.32 | 0.68 | Partial for plasma glucose | | | | | | | Area 24 | 0.46 | 0.54 | 0.28 | 0.72 | 0.41 | 0.59 | Area 25 | 0.40 | 0.61 | 0.21 | 0.79 | 0.41 | 0.59 | Area 32 | 0.51 | 0.50 | 0.31 | 0.69 | 0.45 | 0.56 | Amygdala | 0.46 | 0.55 | 0.32 | 0.68 | 0.33 | 0.68 | Ant. hippocampus | 0.47 | 0.53 | 0.36 | 0.64 | 0.27 | 0.73 | Post. hippocampus | 0.41 | 0.59 | 0.33 | 0.67 | 0.20 | 0.80 | Frontal cortex | 0.39 | 0.61 | 0.18 | 0.82 | 0.45 | 0.55 |
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Areas 24, 25, and 32 = Brodmann areas (anterior cingulate cortex); Ant. = anterior; Post. = posterior; .
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