Research Article

Antioxidant and Anti-Inflammatory Effects of Shungite against Ultraviolet B Irradiation-Induced Skin Damage in Hairless Mice

Table 1

Slight suppression of total white blood cells (WBC) and their differential counts in the mineral-rich shungite-treated group. Shown are the effects of mineral-rich shungite (MRS) and mineral-less shungite (MLS) on the total WBC (a) and their differential counts including neutrophil (b), lymphocyte (c), monocyte (d), basophil (e), and eosinophils (f). Control groups include non-UVB-irradiated group (NC), UVB-irradiated only group (UV), UVB + fullerene C60-treated positive control group (PC), and UVB + olive oil-treated group (OIL), while experimental groups include UVB + mineral-rich shungite-treated group (MRS) and mineral-less shungite-treated group (MLS). Statistical analysis was carried out using analysis of variance (ANOVA) followed by subsequent multiple comparison test (Tukey’s multiple comparisons test) using GraphPad Prism version 5.0. Data were expressed as mean ± SD, .

Units in K/mLNCUVPCOILMRSMLS

Total WBC3.16 ± 0.833.098 ± 0.914.25 ± 1.943.54 ± 2.223.032 ± 0.663.76 ± 1.26
Neutrophil1.12 ± 0.351.326 ± 0.761.59 ± 0.861.31 ± 0.861.03 ± 0.281.41 ± 0.44
Lymphocyte1.97 ± 0.622.094 ± 0.632.34 ± 0.961.99 ± 1.411.82 ± 0.422.13 ± 0.82
Monocyte0.13 ± 0.0710.15 ± 0.900.22 ± 0.110.18 ± 0.130.13 ± 0.040.17 ± 0.07
Eosinophil0.02 ± 0.0130.041 ± 0.0580.076 ± 0.130.05 ± 0.060.034 ± 0.0840.033 ± 0.044
Basophil0.007 ± 0.00480.011 ± 0.0170.027 ± 0.0480.014 ± 0.0170.019 ± 0.0360.013 ± 0.016