Commiphora molmol Modulates Glutamate-Nitric Oxide-cGMP and Nrf2/ARE/HO-1 Pathways and Attenuates Oxidative Stress and Hematological Alterations in Hyperammonemic Rats
Table 2
Effect of C. molmol on ammonia, liver function marker enzymes, and TNF-α in control and hyperammonemic rats.
Control
C. molmol
NH4Cl
NH4Cl + C. molmol
Ammonia (μmol/dL)
75.30 ± 6.23
72.69 ± 4.89
418.20 ± 18.48
136.25 ± 8.79###
ALT (U/L)
28.78 ± 4.25
26.50 ± 2.48
64.81 ± 6.23
36.12 ± 3.14###
AST (U/L)
53.45 ± 4.26
48.16 ± 3.89
132.71 ± 8.49
68.51 ± 6.77###
ALP (U/L)
82.69 ± 6.13
84.26 ± 5.23
179.18 ± 10.26
95.50 ± 7.56###
TNF-α (pg/mL)
32.60 ± 2.42
35.78 ± 3.88
78.59 ± 5.53
48.36 ± 4.33##
Data are expressed as mean ± SEM (). versus control, and ## and ### versus NH4Cl.