Plasma DNA Mediate Autonomic Dysfunctions and White Matter Injuries in Patients with Parkinson’s Disease

Figure 3

The mediation model in this study. Path (a) was defined as the effect of the independent variable (baroreflex sensitivity) on the mediator (nuclear DNA). Path (b) was the effect of the mediator (nuclear DNA) on the dependent variable (left cingulum MD) by controlling the effect of the baroreflex sensitivity. Path (c′) shows the direct path from independent variables (baroreflex sensitivity) to dependent variables (left cingulum MD). The mediation relationship passed the Sobel test after controlling age and sex.