MitoTEMPO Prevents Oxalate Induced Injury in NRK-52E Cells via Inhibiting Mitochondrial Dysfunction and Modulating Oxidative Stress

Figure 2

Mito attenuates oxalate induced cell injury and lipid peroxidation (a, b). (a) Mito decreased oxalate induced LDH release at 3, 6, and 24 hours. (b) Lipid peroxidation was assessed by detecting MDA level in the supernatants of NRK cell lysates. Pretreatment with Mito (1 hour) obviously attenuated MDA generation compared with oxalate induced group. versus control; versus oxalate treated group (: MitoTEMPO).

(a)

(b)