Research Article

Pitaya Extracts Induce Growth Inhibition and Proapoptotic Effects on Human Cell Lines of Breast Cancer via Downregulation of Estrogen Receptor Gene Expression

Figure 4

Effect of PE on cell cycle progression in MCF-7 and MDA-MB-435 cells after 24 and 48 h exposure. Data are presented as mean ± standard deviation of 3 independent experiments, with significant differences between the untreated cells (I) and treated with PE 500 (II) and 1000 (III) μg/mL compared by the Tukey test.