Oxidative Medicine and Cellular Longevity / 2017 / Article / Tab 3

Research Article

Pitaya Extracts Induce Growth Inhibition and Proapoptotic Effects on Human Cell Lines of Breast Cancer via Downregulation of Estrogen Receptor Gene Expression

Table 3

Effect of PE on cell cycle progression in MCF-7 and MDA-MB-435 cells after 24 h and 48 h exposure.

Cell lineIncubation timeCell cycle phasesControl (CT)500 μg/mL1000 μg/mL

MCF-724 hG0/G159.59 ± 0.1663.47 ± 2.0765.02 ± 0.23
S16.91 ± 1.2014.03 ± 0.6114.80 ± 2.36
G2/M19.28 ± 1.8719.77 ± 1.4217.48 ± 3.22
48 hG0/G158.49 ± 0.4565.40 ± 1.1069.61 ± 3.90
S16.45 ± 0.5510.63 ± 0.2513.64 ± 1.71
G2/M22.28 ± 0.9320.19 ± 0.0415.66 ± 3.72

MDA-43524 hG0/G162.30 ± 1.1261.99 ± 1.9961.60 ± 0.64
S14.84 ± 0.4314.93 ± 0.2414.87 ± 0.51
G2/M19.90 ± 1.2919.83 ± 2.0418.88 ± 0.68
48 hG0/G169.64 ± 1.1870.64 ± 0.8070.01 ± 1.85
S11.88 ± 0.8911.30 ± 0.6211.50 ± 0.53
G2/M15.17 ± 1.0315.52 ± 0.5215.76 ± 0.83

The cell cycle phases and quantitative results are illustrated in accordance with the exposure time and PE concentration. The experiment is expressed as mean ± error standard. indicates significant differences from the control group (; ).

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