Research Article
Oxidative Modification of Blood Serum Proteins in Multiple Sclerosis after Interferon Beta and Melatonin Treatment
Table 1
Demographic data of the subjects studied.
| | Group | Control | RRMS INF-beta + MEL | RRMS INF-beta | RRMS untreated |
| | Subject number (n) (total ) | 11 | 25 | 36 | 14 | | Age (years) mean ± SD | 34.54 ± 9.6 | 38.16 ± 8.29 | 39.49 ± 10.16 | 40.65 ± 10.01 | | Female/male number (n) | 6/5 | 18/7 | 26/10 | 7/7 | | EDSS mean ± SD | NA | 1.85 ± 0.75 | 2.52 ± 1.14 | 2.68 ± 1.11 | | Disease duration (years) mean ± SD | NA | 4.89 ± 1.41 | 6.07 ± 3.97 | 0.88 ± 0.65 | | Treatment duration (months) mean ± SD | NA | 29.51 ± 5.03 | 28.18 ± 7.13 | NA | | Number of T2 brain MRI lesions (mean ± SD) | NA | 8.70 ± 7.54 | 9.18 ± 6.56 | 11.11 ± 10.94 | | Number of T1 Gd(+) brain MRI lesions (mean ± SD) | NA | 0.52 ± 0.17 | 0.66 ± 0.65 | 0.86 ± 0.85 |
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NA: nonapplicable. Data are presented as mean ± SD.
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