Research Article

Febuxostat Modulates MAPK/NF-κBp65/TNF-α Signaling in Cardiac Ischemia-Reperfusion Injury

Figure 4

Effect of XOI on cardiac injury and inflammatory markers. (a) CK-MB and LDH; (b) TNF-α and IL-6. IR + control: ischemia-reperfusion control; FEB10 + IR: febuxostat 10 mg/kg/day + ischemia-reperfusion; ALL100 + IR: allopurinol 100 mg/kg/day + ischemia-reperfusion. Data are expressed as the mean ± SEM; in each group. and versus IR + control; ### versus sham. a versus ALL100 + IR.
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