Review Article

Roles and Mechanisms of Herbal Medicine for Diabetic Cardiomyopathy: Current Status and Perspective

Table 2

In vitro studies of herbs in the application of DCM.

DrugDosageExperimental modelReference

Triptolide20 ng/mlHigh-glucose cultured H9c2 rat cardiac cells[64]
C662.5, 5, or 10 μmol/LHigh-glucose cultured H9c2 cells[69]
C662.5, 5, or 10 μmol/LHigh-glucose cultured neonatal rat cardiomyocytes[69]
Resveratrol50 μMHigh-glucose cultured neonatal rat cardiomyocytes[79]
Astragalus polysaccharides0.8 mg/mlHigh-glucose cultured H9c2 cardiomyocytes[85]
Myricitrin25 μg/mlAGE-induced H9c2 cells[90]
Taxifolin20, 40 μg/mlHigh-glucose cultured H9c2 cells[92]
Naringin80 μMHigh-glucose cultured H9c2 cells[96]
Total saponins of Aralia taibaiensis25, 50, and 75 μg/mlG/GO cultured H9c2 cardiomyocytes[109]

C66; Compound (2E, 6E)-2,6-bis (2-(trifluoromethyl)benzylidene) cyclohexanone; AGE: advanced glycation end products; G/GO: 33 mM glucose + 15 mU glucose oxidase.