PPAR-γ Activation Prevents Septic Cardiac Dysfunction via Inhibition of Apoptosis and Necroptosis

Figure 4

Cardiomyocyte apoptosis in septic rats. Myocardiums of rats subjected to CLP with or without pretreatment of rosiglitazone (ROT) or T007 were collected 18 hours after CLP. Apoptotic cardiomyocytes were assessed by terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL). (a, b) TUNEL-positive cells were stained brown and counted. versus sham. ^## versus CLP. Data are presented as mean ± SEM. per group.

(a)

(b)