Exercise Training under Exposure to Low Levels of Fine Particulate Matter: Effects on Heart Oxidative Stress and Extra-to-Intracellular HSP70 Ratio

Table 5

Haematological parameters of mice exposed to fine particulate matter (PM_2.5) submitted to 12 weeks of exercise training.

	CON	PM2.5	MIT	MIT + PM2.5	HIT	HIT + PM2.5	ANOVA ( value)
WBC (10^3·mm^−3)	10.8 ± 2.8	6.8 ± 3.1	8.9 ± 3.3	7.2 ± 3.1	7.6 ± 1.2	6.6 ± 0.8	0.146
LYM 10^3·mm^−3 (%LYM)	8.96 ± 2.38 (83.0 ± 4.4)	5.86 ± 2.87 (84.5 ± 1.5)	7.56 ± 3.13 (83.4 ± 3.2)	6.85 ± 2.68 (82.3 ± 2.4)	6.51 ± 0.93 (84.5 ± 4.5)	5.46 ± 0.81 (82.0 ± 3.0)	0.214
MON 10^3·mm^−3 (%MON)	0.58 ± 0.19 (5.3 ± 0.8)	0.31 ± 0.14 (5.0 ± 0.9)	0.43 ± 0.12 (5.0 ± 1.2)	0.47 ± 0.17 (5.1 ± 0.8)	0.37 ± 0.06 (5.2 ± 0.9)	0.35 ± 0.06 (5.1 ± 0.8)	0.041
GRA 10^3·mm^−3 (%GRA)	1.34 ± 0.56 (12.5 ± 3.8)	0.63 ± 0.31 (9.6 ± 2.8)	0.97 ± 0.19 (11.6 ± 3.2)	0.99 ± 0.30 (12.5 ± 2.5)	0.71 ± 0.50 (10.2 ± 4.9)	0.87 ± 0.15 (13.2 ± 3.1)	0.047
RBC (10^6·mm^−3)	10.5 ± 1.1	7.92 ± 0.4	9.7 ± 1.3	8.94 ± 0.9	7.8 ± 1.7	8.31 ± 0.6	0.220
HGB (g·dL^−1)	17.4 ± 3.9	13.6 ± 1.5	15.8 ± 4.0	14.6 ± 2.9	13.3 ± 5.1	13.2 ± 2.2	0.286
HCT (%)	40.2 ± 1.5	34.5 ± 1.5	39.8 ± 1.5	40.6 ± 4.5	37.1 ± 1.6	37.6 ± 2.9	0.291
PLT (10^3·mm^−3)	1436 ± 329	975 ± 372	1124 ± 364	1157 ± 248	1036 ± 575	906 ± 145	0.210
NEU/LYM ratio (10^3·mm^−3)	0.15 ± 0.05	0.11 ± 0.03	0.14 ± 0.04	0.15 ± 0.03	0.10 ± 0.06	0.16 ± 0.04	0.425

Haematological parameters expressed as mean ± SEM. CON: control group, received 10 μL saline daily, maintained sedentary. MIT: moderate intensity training group, received 10 μL saline daily. HIT: high intensity training group, received 10 μL saline daily. PM_2.5: EXPOSURE group, received 5 μg of PM_2.5 daily, maintained sedentary. MIT + PM_2.5: moderate intensity training group, received 5 μg of PM_2.5 daily. HIT + PM_2.5: high intensity training group, received 5 μg of PM_2.5 daily (n = 5-6 per group). Data analysed by two-way ANOVA followed by Tukey’s post hoc test. values describe here in each variable in terms of the PM_2.5 effect, exercise effect, and interaction, respectively. WBC: white blood cell (, , and ). %LYM: lymphocyte percentage (, , and ). %MON = monocyte percentage (, , and ). %GRA: granulocyte percentage (, , and ). RBC: red blood cells (, , and ). HGB: haemoglobin (, , and ). HCT: haematocrit (, , and ). PLT: platelet total count (, , and ). versus the control group; one-way ANOVA.