A New Natural Antioxidant Mixture Protects against Oxidative and DNA Damage in Endothelial Cell Exposed to Low-Dose Irradiation

Figure 2

RiduROS inhibited ROS generation and restore NO levels after low-dose irradiation. (a) HUVEC were pretreated with RiduROS (0.1–1 μg/mL), then exposed to 0.25 Gy of radiation. After 45 min of incubation, monolayers were harvested and lysed for quantitative determination of ROS. All values are expressed as mean ± SD of arbitrary fluorescence units of three independent experiments. versus 0.25 Gy alone. (b) Supernatants were collected 24 h after irradiation and total levels of nitrate/nitrite were measured. Data are mean ± SD and representatives of three independent experiments and expressed as μmol/L/10⁵ cells. versus control cells; versus 0.25 Gy alone.

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