Oxidative Medicine and Cellular Longevity / 2017 / Article / Fig 5

Research Article

Apocynin Prevents Abnormal Megakaryopoiesis and Platelet Activation Induced by Chronic Stress

Figure 5

Apocynin decreases platelet activation induced by chronic stress. Flow cytometry analyses of (a) GPIIbIIIa activation (JON/A-PE antibody) and (b) P-selectin expression in washed platelets, and percentage of (c) platelet/monocyte, (d) platelet/neuthrophil, and (e) platelet/lymphocyte aggregates in whole blood of control mice (treated with vehicle) and of mice exposed to forced swimming stress with vehicle (FSS) or with Apocynin (FSS + Apocynin). mice/group. , , , and . For each box-plot, the center line illustrates the median and box limits indicate the 25th and 75th percentiles. Data were analyzed by 2-way ANOVA with repeated measures for main effects of treatment and stimuli, followed by a Bonferroni post hoc analysis.

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