Oxidative Medicine and Cellular Longevity / 2017 / Article / Tab 2

Research Article

Mitochondria-Targeted Antioxidant SkQ1 Prevents Anesthesia-Induced Dry Eye Syndrome

Table 2

Pathomorphological characteristics of the cornea in general anesthesia-induced DES.

Corneal compartmentDiagnosisParameterAnesthesia time, h
Control136

EpitheliumSuperficial cell desquamationIncidence, %0100100100
MSS02.3 ± 0.53.6 ± 0.64.3 ± 0.5
Deep layer cell loss (erosion)Incidence, %00100100
MSS002.0 ± 0.94.3 ± 0.6
DenudationIncidence, %0066100
MSS002.0 ± 1.54.0 ± 0.9
Cell degenerationIncidence, %00100100
MSS003.3 ± 0.63.7 ± 0.5
Signs of apoptosisIncidence, %0033100
MSS000.6 ± 0.93.6 ± 0.5
ReepithelizationIncidence, %0000
MSS0000
StromaEdemaIncidence, %0000
MSS0000
Inflammatory infiltrationIncidence, %0000
MSS0000
NeovascularizationIncidence, %0000
MSS0000
EndotheliumVacuolizationIncidence, %0000
MSS0000
Cell lossIncidence, %0000
MSS0000

Incidence and mean severity scores (MSS) were determined as described in Materials and Methods. compared with control.

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