Serum Bilirubin Levels and Promoter Variations in HMOX1 and UGT1A1 Genes in Patients with Fabry Disease

Table 3

Serum bilirubin concentrations in patients with FD and controls according to UGT1A1 genotype.

UGT1A1 genotype	FD	Controls	value
6/6	7.1 [6.1–10.7]	10.2 [8.6–11.4]	0.009
6/7	8.7 [7.1–11]	12.4 [8.5–15.6]	0.053
7/7	9.0 [6.4–15.2]	17.8 [14.7–21.5]	0.025
for trend	0.538	<0.001

Bilirubin expressed in μmol/L as median and IQ range. FD: Fabry disease. Differences in serum bilirubin concentrations across individual UGT1A1 genotypes in FD and controls.