Cardiovascular Protective Effects of Salvianic Acid A on db/db Mice with Elevated Homocysteine Level

Table 3

The methylation status (SAM/SAH ratio) in the liver of the mice at the end of the experiment.

	DM (control)	DM (SAA)	DM (methionine)	DM (methionine + SAA)	Non-DM
SAM (μg/g)	0.101 ± 0.01	0.051 ± 0.003	0.133 ± 0.021	0.089 ± 0.011	0.062 ± 0.007
SAH (μg/g)	0.112 ± 0.027	0.100 ± 0.027	0.156 ± 0.010	0.212 ± 0.024	0.098 ± 0.025
SAM/SAH ratio	1.57 ± 0.75	0.94 ± 0.37	0.86 ± 0.13	0.46 ± 0.08	0.93 ± 0.19

SAM: S-adenosylmethionine; SAH: S-adenosylhomocysteine. All values are expressed as concentration (μg/g) per 1 g of liver tissue. versus the non-DM and DM (SAA) groups. versus the DM (methionine + SAA) group. versus the DM (methionine + SAA) group.